CJC No DAC /Ipamorelin Blend – GHRH/GHRP Synergistic Research Stack
Intro Paragraph (Keyword Rich)
This advanced CJC-1295 No DAC Ipamorelin blend combines a growth hormone-releasing hormone analog with a selective ghrelin mimetic to create a powerful research tool for studying endogenous growth hormone pulsatility. Each vial contains 2mg Mod GRF 1-29 (CJC-1295 without DAC) and 2mg Ipamorelin, formulated to investigate the amplified GH response achieved when GHRH and GH secretagogue pathways are stimulated simultaneously.
Note: For laboratory research and analytical studies only. Not for human consumption, diagnosis, or treatment.
Mechanism of Action & Research Applications
CJC-1295 No DAC (Modified Growth Hormone Releasing Factor 1-29) functions as a GHRH analog with improved pharmacokinetics—specifically the removal of DAC (Drug Affinity Complex) allows for natural pulsatile GH release patterns rather than continuous elevation. Combined with Ipamorelin, a pentapeptide GH secretagogue that mimics ghrelin without affecting cortisol or prolactin, this stack enables precise research into somatotroph cell signaling and IGF-1 modulation.
Primary Research Applications:
- Growth hormone pulsatility studies
- Metabolic rate and lipolysis research
- Somatotropic axis modulation
- Bone density and collagen synthesis assays
- Appetite regulation mechanisms (ghrelin pathway)
Product Specifications
- Composition: CJC-1295 No DAC (2mg) + Ipamorelin (2mg)
- Total Peptide Content: 4mg lyophilized powder per vial
- CJC-1295 No DAC Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
- Ipamorelin Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
- Molecular Weight: ~3367 g/mol (combined)
- Purity: ≥99% (HPLC/MS verified)
- Appearance: White fluffy lyophilized powder
- Solubility: Soluble in bacteriostatic water or sterile saline
- Storage: -20°C (lyophilized), use within 7 days after reconstitution at 2-8°C
The Synergy Advantage: Why Researchers Choose the Blend
Unlike continuous GH stimulation, the CJC-1295 No DAC Ipamorelin combination preserves natural pituitary pulsatility while amplifying peak amplitude. Ipamorelin’s selectivity for the GH secretagogue receptor (GHS-R1a) without significant prolactin or cortisol release makes it superior to non-selective GHRPs for isolated GH pathway studies.
For researchers requiring individual compound titration, see our standalone CJC-1295 No DAC and Ipamorelin listings.
Reconstitution Protocol
Reconstitute this growth hormone research blend with 2ml of bacteriostatic water to achieve a concentration of 1mg/ml per peptide (2mg/ml total). This 1:1 ratio maintains the optimal research standard for studying synergistic effects.
Preparation Requirements:
- Bacteriostatic Water 30ml (multi-dose)
- 1ml Insulin Syringes 31G for precise measurement
- Sterile alcohol prep pads
Important: Allow the lyophilized cake to dissolve naturally without agitation. Peptides of this molecular weight are sensitive to mechanical stress and temperature fluctuations.
Storage & Stability Considerations
The CJC Ipamorelin blend requires strict cold chain maintenance. Lyophilized vials remain stable for 24 months at -20°C protected from light. Once reconstituted, the solution maintains integrity for 5-7 days refrigerated at 2-8°C. Due to the absence of mannitol or other stabilizing excipients in this pure formulation, avoid freezing reconstituted solution to prevent peptide aggregation.
Research Safety & Handling
Handle this GH secretagogue blend in accordance with laboratory safety protocols for bioactive peptides. Use laminar flow hoods for preparation and maintain aseptic technique throughout. This compound is intended for receptor binding studies, cell culture applications, and in-vitro metabolic research only.
Frequently Asked Research Questions
What is the difference between CJC-1295 with DAC vs. No DAC?
CJC-1295 No DAC (Mod GRF 1-29) has a short half-life (~30 minutes) allowing natural GH pulse patterns, while the DAC version creates a long-acting continuous stimulation via albumin binding—different research applications entirely.
Why combine CJC-1295 No DAC with Ipamorelin specifically?
Ipamorelin is the most selective GHRP, avoiding cortisol and prolactin spikes seen with GHRP-2 or GHRP-6, allowing cleaner GH pathway isolation in research settings.
What concentration is optimal for research?
Most protocols utilize the 1:1 ratio provided in this blend (2mg:2mg), reconstituted to 1mg/ml per peptide for flexible dosing matrices.
CJC No Dac / Ipamorelin is a research compound in lyophilized powder form for laboratory research, testing, and analytical applications.
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Compound: CJC No Dac / Ipamorelin
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Quantity: 10 mg
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Purity: ≥99% (HPLC Certified)
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Form: Lyophilized powder
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Appearance: White to off-white powder
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Solubility: Soluble in laboratory-grade sterile water
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COA: Included in product image gallery





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